Research into New Cancer Treatment Options

New cancer treatment options target cancer cell growth

Cancer cells are known to differ from healthy cells, including in their requirements for oxygen and nutrients, their blood supply, their rate of growth and in their ‘immune privileged’ position.

At present, leading research organisations are attempting to develop new medicines that may work on cancer cell metabolism and the ‘immune privileged’ position. However, these new medicines will take a long time to reach the market; they will have unknown side effects and are likely to be expensive.

Using existing, low cost, well tolerated medicines to treat cancer

The Care Oncology Clinic uses a mixture of established tolerable prescription medicines to treat patients with cancer. Data on patient outcomes will be reported.

The Care Oncology Clinic’s treatment is overseen by leading oncologists and evaluates the effectiveness and tolerability of mixtures of established prescription medicines. These medicines target cholesterol, glucose and glycolysis processes, which impact upon the metabolism of the cancer cells and the immune cells surrounding the cancer cells.

The Ultrastructural Anatomy of the Cell

The Ultrastructural Anatomy of the Cell

Reference list

Please click here to see other articles that have been in the press and peer review journals on existing medicines that show positive effect on cancer treatment. Many of these reports cover generic, re-purposed medicines being explored as beneficial to patients, in combination with conventional therapy approaches.

Metabolism and cancer

    • Cancer as a metabolic disease, Seyfried Nutrition and Metabolism, 2010.
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    • Mitochondria and the evolutionary roots of cancer, Davila Phys Biol, 2013.
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    • Cancer metabolism: current perspectives and future direction, Munoz-Pinedo, Cell Death and Disease 2012.
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Lipid metabolism

  • The Role of Statins in Cancer Therapy, Hindler, The Oncologist, 2006.
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  • Statin a day keeps the cancer at bay, Sinh World Journal of Oncology, 2013.
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Glucose metabolism

  • Metformin is Associated with Survival Benefit in Cancer Patients With Concurrent Type 2 Diabetes: A Systemic Review and Meta-Analysis, Ming Yin et al, The Oncologist November 2013.
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  • Diabetes, cancer, and metformin: connections of metabolism and cell proliferation, Gallagher, Annals of the New York Academy of Sciences 2011.
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  • Cancer Risk in Diabetic Patients Treated with Metformin: A systematic Review and Meta-analysis, Noto, PlosOne 2012.
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Glycolysis Inhibition

  • Mebendazole mono-therapy and long term disease control in metastatic adrenocortical carcinoma, Dobrosotskaya, Endocrine Practice 2011.
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  • Mebendazole Elicits a potent anti-tumour Effect on Human Cancer Cell Lines Both in vitro and in Vivo, Roth, Clinical Cancer Research 2002.
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